Innovative and Evidence-Based Bundle Reduces Hospital-Onset C. difficile by 53%

Catherine Adamson, RN, MSN, UC Davis Health, and Julie Wardinsky, RN, BSN, CIC, UC Davis Health


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POSTER - #PI1028

Innovative and Evidence-Based Bundle Reduces Hospital-Onset C. difficile by 53%

Catherine Adamson, RN, MSN, UC Davis Health, and Julie Wardinsky, RN, BSN, CIC, UC Davis Health

Annually, there are 500,000 Clostridium difficile (CDI) cases and 15,000 related deaths in the United States.•UC Davis Health (UCDH), a 625 bed academic acute care hospital, exceeded internal and national hospital-onset CDI (HO-CDI) benchmarks•In 2013 there was no national standardized target. •2015: National Healthcare Safety Network (NHSN) established Standardized Infection Ratio (SIR) goal of 1.0. for HO-CDI•UCDH multi-disciplinary team developed an original CDI prevention bundle combining innovative and evidence based strategies to combat CDI•UCDH team has sustained significant reduction in HO-CDI that has evolved over a period of 5 years.

Reduce and sustain HO-CDI in our UCDH acute care hospital to a SIR less than 1.0 to improve and save lives.

PICO Question
In the academic hospital setting, can the implementation of a multi-pronged innovative and evidence-based CDI prevention bundle decrease and maintain HO-CDI below the SIR?

Design and methods
2013-14: We launched an innovative quality improvement project designed to identify and isolate patients with asymptomatic C. difficilecolonization. These “carriers” are a known reservoir of CDI transmission. While a 20% reduction in HO-CDI was achieved, stakeholders agreed there was more work to be done. With full administrative support, a multi-disciplinary team was chartered in 2017 to “go back to the drawing board,” identify gaps in care, and develop a plan of action.

Implementation plan (See poster)

Outcomes (See poster)

• Combining evidence-based approaches with cutting edge strategies has led to a desirable and sustainable outcome
• Once all bundle elements were fully implemented, our HO-CDI rate and SIR decreased dramatically•We have met and sustained our improvement goals for the past seven quarters
• Beautiful job by our staff of educating our patients with an emphasis on patient safety and protection
• Our team effort, which involved nearly every hospital department, could not have succeeded without the unwavering support of our administration•Vital role of antimicrobial and diagnostic stewardship
• Home grown EMR tools led to faster, more effective tracking and intervening
• When we leverage administrative backing and break down organizational silos to effect change, our patients reap the benefit in the form of lives improved and saved

• Dubberke, E., & Burnham, C. (2015). Diagnosis of Clostridium difficile infection: Treat the patient, not the test. JAMA Internal Medicine, 175(11).
• McDonald, L.C., Gerding, D.N., Johnson, S., Bakken, J.S., Carroll, K.C., Coffin, S.E….Wilcox, M.H. (2018). Clinical practice guidelines for Clostridium difficile infection in adults and children: 2017 update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA), Clinical Infectious Diseases, 66(7), e1-e48.

Gordon and Betty Moore Foundation

UCDH Patient Care Services
UCDH Infection Prevention Steering Committee
UCDH PCS Quality and Safety
UCDH Quality and Safety Clinical Affairs

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