Poster - #UMDOM23 - Clinical Vignettes (case studies)

Herpes invites an unwelcome guest: A case of concomitant herpes simplex virus type 1 (HSV-1) and autoimmune encephalitides

Patton Adderley, MD, Tiffany Chomko, MD, Javier Sanchez, MD, Teresita Casanova, MD, Adam Friedlander, MD

University of Miami/JFK Medical Center Palm Beach Regional GME Consortium West Palm Beach Department of Veterans Affairs

ABSTRACT
HSV-1 encephalitis is a disease that carries significant morbidity and mortality. Evidence shows that 20-30% of these patients go on to develop autoimmune encephalitis; the most common variant in this setting being anti‐NMDA receptor encephalitis. Patient outcomes without immunotherapy are often poor, however early treatment initiation can dramatically improve ones chances of neurological recovery. Therefore, it is important to consider this differential in all patients with HSV encephalitis.